2 Feb Updated guidelines for chronic obstructive pulmonary disease (COPD) highlight changes in diagnosis, strategies for deescalation of therapy, options for nonpharmacologic therapies, and an emphasis on the importance of comorbidities for the management of patients with COPD. The Global Strategy for the. Stay up to date with the latest news from the European Respiratory Society, including current ERS affairs and highlights in industry leading research. 15 March, On 16 March, ERS will join health and patient organisations from all over the world to observe the 11th annual World Sleep Day. This year's more. News. 25 Aug Among selected subjects with COPD, azithromycin taken daily for 1 year, when added to usual treatment, decreased the frequency of exacerbations and . Proportion of Participants Free from Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) for 1 Year, According to Study Group.
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- 3 Aug The Global Initiative for Chronic Obstructive Lung Disease (GOLD), a report produced by the National Heart, Lung, and Blood Institute (NHLBI) and the World Health Organization (WHO), defines an exacerbation of chronic obstructive pulmonary disease (COPD) as "an acute event characterized by a.
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A correction has been published 1. Acute exacerbations adversely affect patients with chronic obstructive pulmonary disease COPD. Macrolide antibiotics benefit patients with a variety of inflammatory airway diseases. We performed a randomized trial to determine whether azithromycin decreased the frequency of exacerbations in participants with COPD who had an increased risk of exacerbations but no hearing impairment, resting tachycardia, or apparent risk of prolongation of the corrected QT interval.
The frequency of exacerbations was 1. The scores on the St. Among selected subjects with COPD, azithromycin taken daily for 1 year, when added to usual treatment, decreased the frequency of exacerbations and improved quality of life but caused hearing decrements in a small percentage of subjects.
Although this intervention could change microbial resistance patterns, the effect of this change is not known. Acute exacerbations of chronic obstructive pulmonary disease COPD result in frequent visits to physicians' offices and emergency rooms and numerous hospitalizations and days lost from work; they also account for a substantial percentage of the cost of treating COPD. Macrolide antibiotics have immunomodulatory, antiinflammatory, and antibacterial effects.
We used a prospective, parallel-group, placebo-controlled design. Participants were randomly assigned, in a 1: Participants were recruited from 17 sites associated with 12 academic health centers in the United States.
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